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C646 has also been used to study the role of p300-mediated gene regulation in neuroscience
Smiles: CC1=CN(C=N1)C1C=C(C=C(C=1)NC(=O)C1C=C2CN(C[C@H](C)C2=CC=1)C1C=NC=NC=1)C(F)(F)F
functions as a neurotoxin
selective and orally bioavailable Wee1 kinase inhibitor with IC50 of 5
GNE-0877 is a highly potent and selective LRRK2 inhibitor
Maleimide-DOTA RAK inhibitor 4 (trans) C646 has also been usedMaleimide DOTA is a non cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1006711 90 5 Molecular Weight: 526. 54 Formula: C22H34N6O9 Chemical Name: 2 [4,7 bis(carboxymethyl) 10 ({[2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethyl]carbamoyl}methyl) 1,4,7,10 tetraazacyclododecan 1 yl]acetic acid Smiles: OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 InChiKey: AUTDIWAXETZSGJ
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