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IL-22 and IL-23R
CU-T12-9 6981 maleate IL-22 and IL-23RCU T12 9 is a specific TLR1 2 agonist with EC50 of 52. 9 nM in HEK Blue hTLR2 SEAP assay. CU T12 9 activates both the innate and the adaptive immune systems. CU T12 9 selectively activates the TLR1 2 heterodimer, not TLR2 6. CU T12 9 signals through NF B and invokes an elevation of the downstream effectors TNF , IL 10, and iNOS. Product information CAS Number: 1821387 73 8 Molecular Weight: 362. 31 Formula: C17H13F3N4O2 Chemical Name: N methyl 4 nitro
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