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K-Ras ligand-Linker Conjugate 5 G 149 50 and 100 µM) inhibits

SKU: 30885139896

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Description

50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells

CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26

Solubility: DMSO: ≥ 100 mg/mL (80

second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity

Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway

K-Ras ligand-Linker Conjugate 5 G 149 50 and 100 µM) inhibitsK Ras ligand Linker Conjugate 5 incorporates a ligand for K Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 5 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information CAS Number: 2378261 85 7 Molecular Weight: 789. 96 Formula: C42H59N7O8

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