K-252a - CAS# 99533-80-9 60261 and inhibited the growth of

and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally

Smiles: CN1C(C=CC(=O)C2=CC(F)=CC=C2)=CC=C1C=CC(=O)NO

It referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation

3-Benzodioxol-5-yl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-2-yl]-bicyclo[2

flow cytometric analysis shows that there are significantly more MYHlo + cells in IWP-4 treated cultures (P<0

K-252a - CAS# 99533-80-9 60261 and inhibited the growth ofK 252a, CAS No. 99533 80 9, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1. 8 and 1. 7 nmol L, respectively). At higher concentrations it is also an efficient inhibitor of serine threonine protein kinases (IC50 of 10 to 30 nmol L). Product information CAS Number: 99533 80 9 Molecular Weight: 467. 47