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20)3/h15-21
Smiles: NCC(O)C1C=CC=CC=1
Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy
LY-404187 does not affect the magnitude or time course of wholecell K+ or Na+ currents in pre frontal cortex (PFC) pyramidal neurons at concentrations of 10 µM
Smiles: COC1C=C(C[C@@H]2COC(=O)[C@@]2(O)CC2C=C(OC)C(O)=CC=2)C=CC=1O
MAGL-IN-1 444296 20)3/h15-21MAGL IN 1 is a potent, selective, reversible and competitive inhibitor of MAGL, with an IC50 of 80 nM. MAGL IN 1 exhibits anti proliferative effects against human breast, colorectal, and ovarian cancer cells. MAGL IN 1 blocks MAGL in cell based as well as in vivo assays. Product information CAS Number: 2324160 91 8 Molecular Weight: 369. 43 Formula: C22H24FNO3 Chemical Name: 4 fluoro 3 {4 [4 (propan 2 yl)benzoyl]piperidine 1 carbonyl}phenol Smiles:
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