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NGB 2904 hydrochloride nedioic Acid STAT5-IN-2 (10 µM

SKU: 36736963688

4.8
USD100.00 USD133.00

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Description

STAT5-IN-2 (10 µM

Smiles: COC1C=C2N=CN=C(NC3C=C(Cl)C(F)=CC=3)C2=CC=1OCCCCCC(=O)NC(COCC1=CN(CCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1)C(=O)NCCCCCC(=O)N1CCN(CC1)C(=O)C1=CC(CC2=NNC(=O)C3C=CC=CC2=3)=CC=C1F

InChi: InChI=1S/C19H20O10/c20-6-11-15(25)17(27)18(28)19(29-11)13-10(23)5-9(22)12(16(13)26)14(24)7-1-3-8(21)4-2-7/h1-5

6(2):192-7

NC1NC(=O)C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C=2N=1

NGB 2904 hydrochloride nedioic Acid STAT5-IN-2 (10 µMNGB 2904 hydrochloride is a potent, selective, orally active and brain penetrated antagonist of dopamine D3 receptor, with a Ki of 1. 4 nM. NGB 2904 hydrochloride shows selectivity for D3 over D2, 5 HT2, 1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 hydrochloride antagonizes Quinpirole stimulated mitogenesis. NGB 2904 hydrochloride can inhibit Cocaine's rewarding effects and Cocaine induced

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