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ICA-105665 Catalog No.:M15782-C 2014:149628

SKU: 2535352213

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Description

2014:149628

for 14 days) strongly inhibits the growth of large pre-established HCT116 colon xenografts

Research Article Volume 2017

Epub 2014 Feb 27

PubMed PMID: 25678665

ICA-105665 Catalog No.:M15782-C 2014:149628ICA 105665 (PF 04895162) is a potent and orally active neuronal Kv7. 2 7. 3 and Kv7. 3 7. 5 potassium channels opener. ICA 105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 M). ICA 105665 can penetrate the blood brain barrier and has antiseizure effects. Product information Molecular Weight: 355. 34 Formula: C19H15F2N3O2 Chemical Name: N (2 cyclopropyl 7 fluoro 4 oxo 3,4 dihydroquinazolin 3 yl) 2

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