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CAS Number: 27741-01-1
regulating autophagy and cell survival
CAS Number: 195514-63-7
is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity
Smiles: CC(C)(C)NC(=O)NC1=NC2=NC(N)=NC=C2C=C1C1C=C(C=C(C=1)OC)OC
A 438079 417 CAS Number: 27741-01-1A 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors
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