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3389/fphar
InChi: InChI=1S/C26H29N7O2/c1-16-2-5-18(6-3-16)33-22-13-27-10-8-19(22)20-12-28-26(31-25(20)33)30-23-7-4-17-14-32(24(35)15-34)11-9-21(17)29-23/h4
Nur77 modulator 1 is a good Nur77 binder (KD = 3
cell growth inhibition is markedly enhanced compared with single-agent treatment
Smiles: CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1C)C(C)(C)C
TAE-1 ethylbenzenesulfonate 3389/fpharIC50: 0. 3 0. 02 M for AChE; 3. 9 0. 2 M for BuChE TAE 1 is an inhibitor of amyloid fibril formation and aggregation. Alzheimers disease (AD), a progressive neurodegenerative disorder, is characterized by the cerebral accumulation of insoluble aggregates of amyloid peptides (A). Although the precise mechanisms governing neuronal loss remains ambiguous, toxicity resulting from A activated pathways is evident. In vitro: In a previous study, the authors
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