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The activity ofGNE-617 hydrochloride is evaluated on a panel 53 non-small cell lung cancer (NSCLC) cell lines in the presence or absence of 10 μM nicotinic acid
IQ 1 thereby diminishes the β-catenin/p300 interaction and prevents β-catenin coactivator switching from CBP to p300
1007/s12263-015-0499-6
ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2
PubMed PMID: 25044422
Tenofovir - CAS# 147127-20-6 r (D-tartrate) The activity ofGNE-617 hydrochloride isTenofovir is an antiretroviral medication used to prevent and treat HIV AIDS and to treat chronic hepatitis B.[1] The active substance is tenofovir, while tenofovir disoproxil is a prodrug that is used because of its better absorption in the gut. Product information CAS Number: 147127 20 6 Molecular Weight: 287. 21 Formula: C9H14N5O4P Synonym: Viread GS 1278 TDF Chemical Name: ({[(2R) 1 (6 amino 9H purin 9 yl)propan 2 yl]oxy}methyl)phosphonic acid
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