RRx-001 7464 InChi: InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H

InChi: InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H

1-4H3/b11-5-/t16-/m0/s1

2 μM and 20 μM reduces IL-1beta secretion by LPS-activated mixed glia cultures after 1 and 3 days of exposure

PF-04217903 phenolsulfonate also inhibits HGF-mediated cell migration and Matrigel invasion in several c-Met–overexpressing tumor cell lines such as human NCI-H441 lung carcinoma and HT29 colon carcinoma with IC50 values comparable with those for inhibition of c-Met phosphorylation in these cell lines (IC50=7-12

InChi: InChI=1S/C118H174N34O35S

RRx-001 7464 InChi: InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13HRRx 001, a hypoxia selective epigenetic agent and studied as a radio and chem sensitizer, triggers apoptosis and overcomes drug resistance in myeloma. RRx 001 exhibits potent anti tumor activity with minimal toxicity. RRx 001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP . RRx 001 is a potent inhibitor of G6PD and shows potent antimalarial activity. Product information CAS Number: 925206 65 1 Molecular Weight: 268. 02