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In a recent study of pancreatic explants
which is associated with significantly reduced STAT3 phosphorylation
CAS Number: 190786-44-8
specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1)
At the molecular level
AP 1903 - CAS# 195514-63-7 size:2mg solid In a recent study ofAP 1903, CAS No. 195514 63 7, also known as Rimiducid, is a lipid permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild type FKBP12 with 1000 fold lower affinity. This agent is used to homodimerize the Fv containing drug binding domains of genetically engineered receptors such as the iCD40
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