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KN-62 has considerable selectivity for P2X7 receptors within the P2 family
Appearance: white to off-white solid powder
This agent also depolymerizes microtubules and may also interfere with amino acid
1-Dimethylethyl)amino]-2-[(3S)-3-[[7-(1
Petrassi HM
BRD PHOTAC-I-3 Catalog No.:M7566-10 KN-62 has considerable selectivity forBRD PHOTAC I 3 is a photoswitchable BET bromodomain degrader (PHOTAC, PHOtochemically TArgeting Chimera). BRD PHOTAC I 3 comprises a ligand for an E3 ligase, a photoswitch, and the BET bromodomain targeting ligand (+) JQ1 (Cat. No. 4499). Exhibits cytotoxicity and degrades BRD4, BRD3 and to a lesser extent BRD2 in lymphoblast cells upon irradiation with 390 nm light, but not in the dark. Product information CAS Number: 2370997 94 5 Molecular Weight: