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(Z)-JIB-04 19726 ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20

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Description

ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20

is a selective inhibitor of γ-secretase

12 h) increases PC12 cellular viability and markedly inhbits H2O2-induced apoptotic cell death

A-395 treatment results in growth inhibition of human tumor cell lines sensitive to SAM-competitive EZH2 inhibitors

Pluripotin (SC-1) decreases cell growth for 7 colon tumor cell lines

(Z)-JIB-04 19726 ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20(Z) JIB 04 (NSC693627) is the Z isomer of JIB 04 that has two forms, E (HY 13953) and Z isomers. (Z) JIB 04 is inactive in epigenetic analysis. Product information CAS Number: 199596 24 2 Molecular Weight: 308. 76 Formula: C17H13ClN4 Chemical Name: 5 chloro 2 [(Z) 2 [phenyl(pyridin 2 yl)methylidene]hydrazin 1 yl]pyridine Smiles: ClC1=CN=C(C=C1)N N=C(\C1=CC=CC=N1) C1C=CC=CC=1 InChiKey: YHHFKWKMXWRVTJ XLNRJJMWSA N InChi: InChI=1S C17H13ClN4 c18 14 9 10

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