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15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8
InChi: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15
6-tetrahydropyridine-4-carboxylic acid hydrochloride
CC(CCCN(CC)CC)NC1=CC=NC2=CC(Cl)=CC=C21
E J Bowman
A-381393 Size:Contact [email protected] for quotation 15-22)21(27)26-14-16-5-7-25-8-6-16/h1-8A 381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist, with Kis of 1. 5, 1. 9 and 1. 6 nM for human dopamine D4. 4, D4. 2, and D4. 7 receptor, respectively, >2700 fold selectivity over D1, D2, D3 and D5 dopamine receptors. A 381393 shows moderate affinity for 5 HT2A (Ki, 370 nM). Product information CAS Number: 726174 00 1 Molecular Weight: 320. 43 Formula: C20H24N4 Chemical Name: 2 {[4 (3,4 dimethylphenyl)piperazin 1
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