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TLR3 and MDA5 signalling
InChiKey: UOZVVPXKJGOFIG-UHFFFAOYSA-N
is a DGKalpha inhibitor and serotonin receptor antagonist
RS-127445 administrated orally with 1 to 30 mg/kg also dose -dependently reduce the restraint stress-induced defecation in native and TNBS-treated rats
5(11)12)2-4(9)10/h3-8
Mifepristone ne Bromide TLR3 and MDA5 signallingMifepristone is a synthetic steroid compound used as a pharmaceutical. It is used as an abortifacient in the first two months of pregnancy, and in smaller doses as an emergency contraceptive. During early trials, it was known as RU 486, its designation at the Roussel Uclaf company, which designed the drug. The drug was initially made available in France, and other countries then followedoften amid controversy. It is marketed under tradenames Mifegyne
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