![PF-03716556 Size:2mg solid Smiles: [O-][N+](=O)C1C=CC(=CC=1)NC1N=C(N=C(N=1)N1CCOCC1)N1CCOCC1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M7822_1619054295.gif?v=1629178569)
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Smiles: [O-][N+](=O)C1C=CC(=CC=1)NC1N=C(N=C(N=1)N1CCOCC1)N1CCOCC1
PubMed PMID: 20646461
CAS Number: 1202402-40-1
IC50 ~75 μM)
WEHI-539 hydrochloride
PF-03716556 Size:2mg solid Smiles: [O-][N+](=O)C1C=CC(=CC=1)NC1N=C(N=C(N=1)N1CCOCC1)N1CCOCC1PF 03716556 is a potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. PF 03716556 demonstrated 3 fold greater inhibitory activity than revaprazan. PF 03716556 did not display any species differences, exhibiting highly selective profile including the canine kidney Na(+), K(+) ATPase. Kinetics experiments revealed that PF 03716556 has a competitive and reversible mode of action. Product information CAS Number:
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