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LP-533401 Size:Contact [email protected] for quotation activating caspase

SKU: 35495835013

4.6
USD100.00 USD135.00

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Description

activating caspase

Blockade of high mobility group box-1 signaling via the receptor for advanced glycation end-products ameliorates inflammatory damage after acute intracerebral hemorrhage

CAS Number: 215589-63-2

CAS Number: 780763-95-3

InChiKey: HQUPLSLYZHKKQT-WVVFQGGUSA-N

LP-533401 Size:Contact [email protected] for quotation activating caspaseLP 533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. LP 533401 completely inhibits serotonin production in Tph1expressing cells (RBL2H3 cells) at a dose of 1 M. Oral administration once daily for up to 6 weeks of this small molecule prevents the development of and fully rescues, in a dose dependent manner, osteoporosis in ovariectomized rodents because of an isolated increase in bone formation.

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