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Enzastaurin - CAS# 170364-57-5 0280 PubMed PMID: 10822275

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Description

PubMed PMID: 10822275

CAS Number: 440122-66-7

CAS Number: 457961-34-1

autophosphorylates and initiates splicing of XBP1 mRNA

957054-33-0 (mesylate)

Enzastaurin - CAS# 170364-57-5 0280 PubMed PMID: 10822275Enzastaurin, CAS No. 170364 57 5, also known as DB 102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) stimulated neo angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Product information CAS Number:

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