COMPOUND 401 - CAS# 168425-64-7 033 4]triazin-7-yl)cyclohexanecarboxylic acid

4]triazin-7-yl)cyclohexanecarboxylic acid

Currently it is in Phase I clinical trials for advanced head and neck

Qing (Acton

8 nM) very similar to that of Chrysamine-G

In mice bearing Colo-205 colon carcinoma xenografts (p16 deleted)

COMPOUND 401 - CAS# 168425-64-7 033 4]triazin-7-yl)cyclohexanecarboxylic acidCompound 401, CAS No. 168425 64 7, is a potent and selective inhibitor of DNA dependent protein kinase (DNA PK) and mammalian target of rapamycin (mTOR) (IC50 values are 0. 28 and 5. 3 M respectively). Product information CAS Number: 168425 64 7 Molecular Weight: 281. 31 Formula: C16H15N3O2 Synonym: Compound 401 Compound 401 Compound401 Chemical Name: 2 (4 Morpholinyl) 4H pyrimido[2,1 a]isoquinolin 4 one Smiles: O=C1C=C(N=C2C3=CC=CC=C3C=CN21)N1CCOCC1