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RITA induces p53 but does not via DNA damage-signaling pathway
Formula: C11H14ClNO3
42(5):1822-1836
4-((4-(((4-amino-2
Napabucasin inhibits PaCa-2 xenograft tumor growth in mice
ATP (disodium salt) quantel RITA induces p53 but doesRO4987655, also known as CH4987655, is an orally active small molecule, targeting mitogen activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity. MEK inhibitor RO4987655 binds to and inhibits MEK, which may result in the inhibition of MEK dependent cell signaling and the inhibition of tumor cell proliferation. MEK, a dual specificity threonine tyrosine kinase, is a key component of the RAS RAF MEK ERK signaling
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