PF-04859989 hydrochloride Catalog No.:M30145-C COCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=CC=CC=CC2=[N+](CCOCCOCCOCCOCCOCCC(O)=O)C3=CC=CC=C3C2(C)C)C(C)(C)C2=CC=CC=C12

COCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=CC=CC=CC2=[N+](CCOCCOCCOCCOCCOCCC(O)=O)C3=CC=CC=C3C2(C)C)C(C)(C)C2=CC=CC=C12

Facile synthesis of a water-soluble bidentate pyridine–acid ligand and its application in quantifying bovine serum albumin by fluorescence spectroscopy

USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB)

InChi: InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43

but Octreotide alone does not in PCK rats

PF-04859989 hydrochloride Catalog No.:M30145-C COCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=CC=CC=CC2=[N+](CCOCCOCCOCCOCCOCCC(O)=O)C3=CC=CC=C3C2(C)C)C(C)(C)C2=CC=CC=C12PF 04859989 hydrochloride is a brain penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF 04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 M, respectively). Product information CAS Number: 177943 33 8 Molecular Weight: 214. 65 Formula: C9H11ClN2O2 Chemical Name: (3S) 3 amino 1 hydroxy 1,2,3,4 tetrahydroquinolin 2 one