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GSK-2981278 - CAS# 1474110-21-8 Catalog No.:M6485-10 KB-R7943 mesylate blocks NMDAR-mediated ion

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Description

KB-R7943 mesylate blocks NMDAR-mediated ion currents

Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT

SSR128129E inhibits FGF2-induced EC proliferation with an IC50 of 31±1

which is structurally an analogue of naproxen

Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad

GSK-2981278 - CAS# 1474110-21-8 Catalog No.:M6485-10 KB-R7943 mesylate blocks NMDAR-mediated ionGSK 2981278, CAS No. 1474110 21 8, is a highly potent and selective inverse agonist of retinoic acid receptor related orphan receptor gamma (ROR gamma). GSK 2981278 is a strong ROR selective inverse agonist that inhibits activation of the il17 promoter. GSK 2981278 robustly inhibits ROR mediated cytokine production at both the mRNA and protein level. GSK 2981278 attenuates inflammation in a mouse model of psoriasis. Topical treatment with GSK 2981278

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