Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
Smiles: CC(C)=CCC1=C(OC2=C3C=CC(C)(C)OC3=CC(O)=C2C1=O)C1=CC=C(O)C=C1O
CAS Number: 4936-47-4
Formula: C13H9N9O
InChi: InChI=1S/C33H35N7O6/c1-8-28(41)38-24-16-22(12-10-18(24)2)37-33-35-17-23(30(34-4)40-33)32(43)39-25-15-21(11-9-19(25)3)36-31(42)20-13-26(44-5)29(46-7)27(14-20)45-6/h8-17H
Molecular Weight: 783
MK-2461 1762 Smiles: CC(C)=CCC1=C(OC2=C3C=CC(C)(C)OC3=CC(O)=C2C1=O)C1=CC=C(O)C=C1OMK 2461 is a novel ATP competitive multitargeted inhibitor of activated c Met with a mean IC50 of 2. 5 nM. IC50 value: 2. 5 nM Target: c Metin vitro: MK 2461 inhibits the kinase activity of human c Met with a mean IC50 of 2. 5 nM in the presence of 50 M ATP. Ron (IC50 = 7 nM) and Flt1 (IC50 = 10 nM) are inhibited by MK 2461 with similar potencies to c Met (IC50 = 2. 5 nM), whereas nine other kinases, including FGFR1, FGFR2, FGFR3, PDGFR, KDR, Flt3,
US$ 195.00
US$ 23.37
US$ 105.45
US$ 167.50
US$ 77.57
US$ 255.00
US$ 537.50
US$ 17.42