Nomifensine-d3 maleate - CAS# 1795140-41-8 14625 Smiles: CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@@H](COC(C2C=CC=CC=2)(C2C=CC(=CC=2)OC)C2C=CC(=CC=2)OC)O[C@H]1N1C=NC2C(NC(=O)C3C=CC=CC=3)=NC=NC1=2

Smiles: CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@@H](COC(C2C=CC=CC=2)(C2C=CC(=CC=2)OC)C2C=CC(=CC=2)OC)O[C@H]1N1C=NC2C(NC(=O)C3C=CC=CC=3)=NC=NC1=2

Solubility: DMSO : 31 mg/mL (90

Water: 53 mg/mL(98

InChi: InChI=1S/C24H34O10S2/c1-21-3-7-23(8-4-21)35(25

Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y

Nomifensine-d3 maleate - CAS# 1795140-41-8 14625 Smiles: CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@@H](COC(C2C=CC=CC=2)(C2C=CC(=CC=2)OC)C2C=CC(=CC=2)OC)O[C@H]1N1C=NC2C(NC(=O)C3C=CC=CC=3)=NC=NC1=2Nomifensine d3 (() Nomifensine d3) maleate is the deuterium labeled Nomifensine maleate (HY B1110A). Nomifensine (() Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5 HT in rat brain synaptosomes, with IC50 values of 6. 6 nM, 48 nM and 830 nM, and Ki values of 4. 7 nM, 26 nM and 4000 nM, respectively. Nomifensine shows low or ineffective binding activity to dopamine D2, 1