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PRMT6 and CARM1 (IC50 are 166
) inhibits the growth of a human tumor xenograft in mice
WS6 was intraperitoneally (IP) dosed to mice 5 mg/kg every other day
CAS Number: 1415800-43-9
2015 Dec 9
TRX-818 - CAS# 1256037-58-7 039 PRMT6 and CARM1 (IC50 areTRX 818, also known as Foslinanib, CVM 1118, CAS No. 1256037 58 7, is an orally bioavailable agent with potential antineoplastic and anti vasculogenic mimicry (VM) activities. Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated, TRX 818, upon oral administration appears to induce cancer cell apoptosis and inhibits cancer cell proliferation. This agent also prevents tumor cell VM