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ARD-2128 (20 mg/kg
Formula: C18H14Cl4N2O
InChiKey: VWCCHJFFYCGXFL-UHFFFAOYSA-N
and cell cycle arrest of MLL-AF6-transformed cells
Formula: C21H30FN3O2
Chlorpyrifos 10 TFA ARD-2128 (20 mg/kgChlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression. Product