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ULK1 inhibition results in accumulation of stalled early autophagosomal structures
14(19):3101-11
Cardiac ion channel current modulation by the CFTR inhibitor GlyH-101
Compound401
2020 Jul-Aug
TBK1 PROTAC® 3i - CAS# 2052306-13-3 ctinib ULK1 inhibition results in accumulationTBK1 PROTAC 3i, CAS No. 2052306 13 3, is a Potent TANK binding kinase 1 (TBK1) Degrader. It exhibits >50 fold selectivity for TBK1 over the closely related IKK. It comprises a ligand for von Hippel Lindau (VHL) protein joined by a linker to a TBK1 targeting moiety. It brings about near complete degradation of TBK1 in mutant K Ras and wild type cancer cell lines with no significant effect of proliferation. Product information CAS Number: 2052306 13 3
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