L-Buthionine-(S, R)-sulfoximine Size:10mg solid InChi: InChI=1S/C26H29N5O3S/c1-5-24-29-25-19(4)28-18(3)16-23(25)31(24)21-10-8-20(9-11-21)14-15-27-26(32)30-35(33

InChi: InChI=1S/C26H29N5O3S/c1-5-24-29-25-19(4)28-18(3)16-23(25)31(24)21-10-8-20(9-11-21)14-15-27-26(32)30-35(33

InChi: InChI=1S/C21H22Cl2N4O2/c1-12(2)26-20-8-16(17(23)10-25-20)14-7-18(24-9-14)21(29)27-19(11-28)13-4-3-5-15(22)6-13/h3-10

Exposures (AUC) increases in a less than dose-proportional manner from 23 μM•h at 5 mg/kg to 362 μM•h at 500 mg/kg

Vatalanib also inhibits Flk

Semapimod tetrahydrochloride inhibits TLR4 signaling (IC50≈0

L-Buthionine-(S, R)-sulfoximine Size:10mg solid InChi: InChI=1S/C26H29N5O3S/c1-5-24-29-25-19(4)28-18(3)16-23(25)31(24)21-10-8-20(9-11-21)14-15-27-26(32)30-35(33L Buthionine (S, R) sulfoximine is a cell permeable, potent, fast acting and irreversible inhibitor of g glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L Buthionine (S, R) sulfoximine on melanoma, breast and ovarian tumor specimens are 1. 9 M, 8. 6 M, and 29 M, respectively. Product information CAS Number: 83730 53 4 Molecular Weight: 222. 31 Formula: C8H18N2O3S Synonym: L Buthionine sulfoximine L BSO Chemical