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RAS inhibitor Abd-7 Size:Contact [email protected] for quotation 3-benzoxazol-6-yl)acetamide

SKU: 68105962284

4.8
USD100.00 USD138.00

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Description

3-benzoxazol-6-yl)acetamide

Chemical Name: 2-(4-{4-[(5S)-5-(acetamidomethyl)-2-oxo-1

SB228357 (0-10 mg/kg

4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide

with IC50 of 26±3 nM (n=21)

RAS inhibitor Abd-7 Size:Contact [email protected] for quotation 3-benzoxazol-6-yl)acetamideRAS inhibitor Abd 7, a potent RAS binding compound (Kd=51 nM), is a RAS effector protein protein interaction (PPI) inhibitor. RAS inhibitor Abd 7 interacts with RAS inside the cells, prevents RAS effector interactions and inhibits endogenous RAS dependent signaling. RAS inhibitor Abd 7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V. Product information CAS Number: 2351843 48 4 Molecular

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