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APTO-253 eptor Agonist 3×25 mg/kg/week) significantly reduces tumor

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Description

3×25 mg/kg/week) significantly reduces tumor growth rates and lowers tumor weights in the L3

Dihexa reverses scopolamine-dependent spatial learning deficits

N-dimethyl-3-thioxanthen-9-ylidenepropan-1-amine

When screened in a single point assay at 10 μM against a Cerep receptor and enzyme panel only one target is inhibited >50% (PDE3

14(1):14-22

APTO-253 eptor Agonist 3×25 mg/kg/week) significantly reduces tumorAPTO 253 (LOR 253, LT 253) inhibits c Myc expression and selectively induces CDKN1A (p21), promotes G0 G1 cell cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO 253 is also an inducer of KLF4 (Krppel like factor 4). Product information CAS Number: 916151 99 0 Molecular Weight: 367. 38 Formula: C22H14FN5 Chemical Name: 2 (5 fluoro 2 methyl 1H indol 3 yl) 1H imidazo[4,5 f][1,10]phenanthroline Smiles:

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