Purvalanol A - CAS# 212844-53-6 181 is a potent and selective

is a potent and selective deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2

Smiles: O=S(=O)(CC1CS1)C1C=CC(=CC=1)OC1C=CC=CC=1

TRX818 sodium

Pressler ML

VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvation

Purvalanol A - CAS# 212844-53-6 181 is a potent and selectivePurvalanol A, CAS No. 212844 53 6, is a potent CDK inhibitor, which effectively suppresses Src mediated transformation by inhibiting both CDKs and c Src. indicating that the activation of CDKs contributes to the c Src transformation. Purvalanol A suppressed the c Src activity as effectively as the Src selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced