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GW-7647 (100 nM) causes a 24% reduction in AQP9 protein abundance in HepG2 cells
chrysin is reported to be an aromatase inhibitor in vitro
Epub 2011 Mar 2
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
5-1(3(7)8)2(6)4(9)10/h4-13
Flavopiridol (Alvocidib) cadesine GW-7647 (100 nM) causes aAlvocidib is a synthetic N methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin dependent kinases (CDKs) and by down regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check for active clinical trials or closed clinical
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