UPF-648 Sodium Salt 436 GW501516 is shown to be

GW501516 is shown to be the most potent and selective PPARα agonists known with an EC50 of 1

GABOB (beta-hydroxy-GABA)

MEK inhibitors: the chemistry and biological activity of U0126

TPI-1 also inhibits B16 tumor growth and prolongs tumor mice survival as a tolerated s

4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea

UPF-648 Sodium Salt 436 GW501516 is shown to beUPF 648 is a potent kynurenine 3 monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 10% KMO inhibition); ineffective at blocking KAT activity. IC50 value: 1 uM(81 10 % inhibition) Target: KMO inhibitor in vitro: BFF 122 inhibited KAT activity almost completely at both 1 and 0. 1 mM. The effect was still remarkable at 0. 01 mM (70 1 % inhibition). Product information CAS Number: 1465017 87 1 Molecular Weight: 281. 07 Formula: