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Pseudolaric Acid B 860 AT7519 shows potent antiproliferative activity

SKU: 85167643440

4.3
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Description

AT7519 shows potent antiproliferative activity in a variety of human tumor cell lines such as SW620

InChiKey: KPBNHDGDUADAGP-VAWYXSNFSA-N

39)/t25-/m0/s1

Peter H Nibbering

Tumors with wild-type p53 and mdm2 gene amplification will respond best to therapy with Nutlin-3a

Pseudolaric Acid B 860 AT7519 shows potent antiproliferative activityPseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi Gorden (pinaceae), has anti cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest. Pseudolaric Acid B induces autophagy. Product information CAS Number: 82508 31 4 Molecular Weight: 432. 46 Formula: C23H28O8 Chemical Name:

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