InChiKey: RKLJJDFIWWRTEJ-UHFFFAOYSA-N
24 hours) significantly reduces both α-SMA and palladin expression that is enhanced by TWEAK in Primary human dermal fibroblasts
Environ Toxicol Pharmacol
Formula: C12H12N2O2S
produces a significant reduction of the immobility time (F2
FM-381 oxetine hydrochloride hemihydrate InChiKey: RKLJJDFIWWRTEJ-UHFFFAOYSA-NFM 381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM 381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600 fold selectivity over JAK1, JAK2 and TYK2, respectively. Product information CAS Number: 2226521 65 7 Molecular Weight: 428. 49 Formula: C24H24N6O2 Chemical Name: (2E) 2 cyano 3 (5 {3 cyclohexyl 3, 5, 8, 10 tetraazatricyclo[7. 3. 0. 0, ]dodeca 1, 4, 6, 8, 11 pentaen 4 yl}furan 2 yl) N, N dimethylprop 2