Hederagenin bactin Smiles: COC1=CC=C2C3=C(C4=CC=CC=C4C=C13)C(=O)N(CCN1CCN(CCNC(=O)C3C=CC(N)=CC=3)CC1)C2=O

Smiles: COC1=CC=C2C3=C(C4=CC=CC=C4C=C13)C(=O)N(CCN1CCN(CCNC(=O)C3C=CC(N)=CC=3)CC1)C2=O

ClH/c1-10-3-9-4-11(2

Abstract 4772: Efficacy of VT-464

Chemical Name: 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2

13a-secoberbin-13a-one

Hederagenin bactin Smiles: COC1=CC=C2C3=C(C4=CC=CC=C4C=C13)C(=O)N(CCN1CCN(CCNC(=O)C3C=CC(N)=CC=3)CC1)C2=OHederagenin is a triterpenoid saponin. It can inhibit LPS stimulated expression of iNOS, COX 2, and NF BHederagenin can Exhibits multiple pharmacological activities in the treatment of hyperlipidemia, antilipid peroxidation, antiplatelet aggregation, liver protection, antidepression, anti inflammation. In vitro: 1) Hederagenin can correct the imbalance of endothelial function by inhibiting the release of large amounts of iNOS and increasing eNOS