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AM-2394 II Degrader-3 CAS Number: 303-98-0

SKU: 95020044795

4.3
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Description

CAS Number: 303-98-0

Chemical Name: 4-cyclohexyl-2-{[2-nitro-4-(trifluoromethyl)phenyl]sulfanyl}-6-oxo-1

displaying 13 to 15-fold more potent inhibition of survival of the WT cells than the CRBN-/- cells

InChiKey: KCPHXRBKBLJJJJ-UHFFFAOYSA-N

IhERG inhibition by KB-R7943 exhibits both time- and voltage-dependence but shows no preference for inactivated over activated channels

AM-2394 II Degrader-3 CAS Number: 303-98-0AM 2394 is a structurally distinct glucokinase activator (GKA). AM 2394 activates glucokinase (GK) with an EC50 of 60 nM. Product information CAS Number: 1442684 77 6 Molecular Weight: 423. 47 Formula: C22H25N5O4 Chemical Name: 1 [6' (2 hydroxy 2 methylpropoxy) 4 [(5 methylpyridin 3 yl)oxy] [3,3' bipyridin] 6 yl] 3 methylurea Smiles: CC1C=C(C=NC=1)OC1C=C(NC(=O)NC)N=CC=1C1C=NC(=CC=1)OCC(C)(C)O InChiKey: QUISANLDBDCMPD UHFFFAOYSA N InChi: InChI=1S

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