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CHMFL-ABL-121 Catalog No.:M27849-C The lysine catabolite saccharopine impairs

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Description

The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis

InChi: InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5

Sparsentan causes a significant lowering of blood pressure at the lowest dose tested (10 µmol/kg/day) in spontaneously hypertensive rats

AG-120 (racemic)

InChi: InChI=1S/C17H16N2O3/c1-10-16(11-3-6-13(22-2)7-4-11)17(19-18-10)14-8-5-12(20)9-15(14)21/h3-9

CHMFL-ABL-121 Catalog No.:M27849-C The lysine catabolite saccharopine impairsCHMFL ABL 121 is a highly potent type II ABL kinase inhibitor with IC50s of 2 nM and 0. 2 nM against purified inactive ABL wt and T315I kinase protein, respectively. Product information CAS Number: 2270879 07 5 Molecular Weight: 580. 67 Formula: C30H31F3N6OS Chemical Name: N {4 [(4 methylpiperazin 1 yl)methyl] 3 (trifluoromethyl)phenyl} 3 ({3 [(E) 2 (pyridin 2 yl)ethenyl] 1H indazol 6 yl}sulfanyl)propanamide Smiles:

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