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BML-284 (10 µM
AUY-922 (500 nM) in combination with NSC 118218 more effectively induces apoptosis in cells in co-culture than either drug alone
also known as CEP-18770
is a small molecule with potential antineoplastic and antiangiogenic activities
a potent inhibitor of the epidermal growth factor receptor
TGR5 Receptor Agonist acangelicin BML-284 (10 µMTGR5 receptor agonist, a potent TGR5 (GPCR19) agonist, showed improved potency in the U2 OS cell assay (pEC50 = 6. 8) and in melanophore cells (pEC50 = 7. 5). Product information CAS Number: 1197300 24 5 Molecular Weight: 361. 22 Formula: C18H14Cl2N2O2 Synonym: CCDC MDK00245 Chemical Name: 3 (2 chlorophenyl) N (4 chlorophenyl) N,5 dimethyl 4 isoxazolecarboxamide Smiles: CC1ON=C(C=1C(=O)N(C)C1C=CC(Cl)=CC=1)C1=CC=CC=C1Cl InChiKey: IGRCWJPBLWGNPX
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