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SU14813 was developed as a next-generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles
Chemical Name: 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2
2009 Jun 11
it markedly augments the capacity of HGF at 1
Epub 2009 Apr 7
NSC-207895 - CAS# 58131-57-0 Catalog No.:M12819-10 SU14813 was developed as aNSC 207895 (XI 006), a DNA damaging agent, is an anticancer agent and p53 activator. Product information CAS Number: 58131 57 0 Molecular Weight: 279. 25 Formula: C11H13N5O4 Chemical Name: 7 (4 methylpiperazin 1 yl) 4 nitro 2, 1, 3 benzoxadiazol 1 ium 1 olate Smiles: CN1CCN(CC1)C1=CC=C(C2=NO[N+]([O ])=C21)[N+]([O ])=O InChiKey: MWFZDJLPWDCQIL UHFFFAOYSA N InChi: InChI=1S C11H13N5O4 c1 13 4 6 14(7 5 13)9 3 2 8(15(17)18)10 11(9)16(19)20 12 10 h2 3H,4