NF-56-EJ40 014olygalasaponin XXXI Chemical Name: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

Chemical Name: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase

Smiles: C[C@@H]1C/C(=C\C)/C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@]1(C)O)[C@@H]32

COC1=CC(=CC=C1NC1C2=CC=CC=C2N=C2C=CC=CC2=1)NS(C)(=O)=O

herbicide agent

NF-56-EJ40 014olygalasaponin XXXI Chemical Name: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamideNF 56 EJ40 is a potent, high affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF 56 EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17. 4 nM. Product information CAS Number: 2380230 73 7 Molecular Weight: 443. 54 Formula: C27H29N3O3 Chemical Name: 2 (2 {4' [(4 methylpiperazin 1 yl)methyl] [1,1' biphenyl] 3 amido}phenyl)acetic acid