Thalidomide-NH-amido-C2-NH2 11344 This blocks the interaction between

This blocks the interaction between the hRRM1 and hRRM2 subunits and interferes with the assembly of the active hRRM1/hRRM2 complex of RNR

4)24(33)12-17-34(25

and it activates a Th1-type pathway (IL-12

62)38-12-5-4-9-34(38)51-41-32(46)27-50-45(53-41)52-33-14-13-30(26-37(33)63-3)55-19-17-54(18-20-55)21-23-65-25-24-64-22-16-47-39(57)28-49-35-10-6-8-31-40(35)44(60)56(43(31)59)36-11-7-15-48-42(36)58/h4-6

InChi: InChI=1S/C26H21FN2O3/c1-17(30)29(16-19-11-13-20(27)14-12-19)24-23(28-15-18-7-3-2-4-8-18)25(31)21-9-5-6-10-22(21)26(24)32/h2-14

Thalidomide-NH-amido-C2-NH2 11344 This blocks the interaction betweenThalidomide NH amido C2 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 373. 36 Formula: C17H19N5O5 Chemical Name: N (2 aminoethyl) 2 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4 yl]amino}acetamide Smiles: NCCNC(=O)CNC1C=CC=C2C=1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: ICFVWGDJVQUIGZ UHFFFAOYSA N