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Characterizing the PK/PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207
CAS Number: 51803-68-0
CC(C)NC[C@H](C1=CC=C(Cl)C=C1)C(=O)N1CCN(CC1)C1=NC=NC2[C@H](O)C[C@@H](C)C=21
5 and 2 mg/kg once daily dosing
decreases CDCA-induced FXR activation with IC50s of 17 and 15 μM for Z- and E-Guggulsterone
L-670, 596 Size:Contact [email protected] for quotation Characterizing the PK/PD relationship forProduct information CAS Number: 121083 05 4 Molecular Weight: 433. 47 Formula: C22H21F2NO4S Chemical Name: 2 [(1R) 6,8 difluoro 9 [(4 methanesulfonylphenyl)methyl] 2,3,4,9 tetrahydro 1H carbazol 1 yl]acetic acid Smiles: CS(=O)(=O)C1C=CC(CN2C3[C@@H](CC(O)=O)CCCC=3C3=CC(F)=CC(F)=C23)=CC=1 InChiKey: GMJWAIMJHBTYPD CQSZACIVSA N InChi: InChI=1S C22H21F2NO4S c1 30(28,29)16 7 5 13(6 8 16)12 25 21 14(9 20(26)27)3 2 4 17(21)18 10 15(23)11 19(24)22(18)25 h5
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